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deoxyadenylic acid
Deoxyadenosine monophosphate, a hydrolysis product of DNA, differing from adenylic acid in containing deoxyribose in place of ribose. SYN: adenine deoxyribonucleotide.
deoxybarbiturate
A barbiturate compound lacking the oxygen atom at the #2 position in the ring; example of a d. is the antiepileptic drug, primidone. SEE ALSO: barbiturate.
deoxycholate
A salt or ester of deoxycholic acid.
deoxycholic acid
7-D.; 3α,12α-dihydroxy-5β-cholanic acid; a bile acid and choleretic; used in biochemical preparations as a detergent.
deoxycoformycin
A purine analog which acts as an antimetabolite; potent inhibitor of adenosine deaminase. Used as an antineoplastic agent. SEE ALSO: pentostatin.
deoxycorticosterone
An adrenocortical steroid, principally a biosynthetic precursor of corticosterone, that occasionally appears in adrenocortical secretions; a potent mineralocorticoid with no ...
deoxycortone
SYN: deoxycorticosterone.
deoxycytidine
2′-Deoxyribosylcytosine, one of the four major nucleosides of DNA (the others being deoxyadenosine, deoxyguanosine, and thymidine).
deoxycytidylic acid
Deoxycytidine monophosphate, a hydrolysis product of DNA.
deoxyepinephrine
A sympathomimetic amine used as a vasoconstrictor.
deoxyguanosine
2′-Deoxyribosylguanine, one of the four major nucleosides of DNA (the others being deoxyadenosine, deoxycytidine, and thymidine). Found to accumulate in individuals with ...
deoxyguanylic acid
Deoxyguanosine monophosphate, a hydrolysis product of DNA. SYN: guanine deoxyribonucleotide.
Deoxyhemoglobin
The form of hemoglobin without oxygen, the predominant protein in red blood cells. Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygen-loaded form it is ...
deoxyhexose
A 6-carbon deoxy-sugar in which one OH is replaced by H.
deoxynucleoside
See deoxyribonucleoside.
deoxynucleotide
See deoxyribonucleoside.
deoxypentose
A 5-carbon deoxy-sugar in which one OH is replaced by H.
deoxyriboaldolase
SYN: deoxyribosephosphate aldolase.
deoxyribodipyrimidine photolyase
An enzyme in yeast that is activated by light, whereupon it can reverse a previous photochemical reaction by cleaving the cyclobutane ring of the thymine dimer. SYN: ...
deoxyribonuclease
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA. SEE ALSO: endonuclease, nuclease. - acid d. SYN: d. II. - d. I, DNase I an endonuclease that cleaves ...
deoxyribonucleic acid
The type of nucleic acid containing deoxyribose as the sugar component and found principally in the nuclei ( chromatin, chromosomes) and mitochondria of animal and plant cells, ...
Deoxyribonucleic acid (DNA)
One of two types of molecules that encode genetic information. (The other is RNA. In humans DNA is the genetic material; RNA is transcribed from it. In some other organisms, RNA ...
deoxyribonucleoprotein
The complex of DNA and protein in which DNA is usually found upon cell disruption and isolation.
deoxyribonucleoside
A nucleoside component of DNA containing 2-deoxy-d-ribose; the condensation product of deoxy-d-ribose with purines or pyrimidines.
deoxyribonucleotide
A nucleotide component of DNA containing 2-deoxy-d-ribose; the phosphoric ester of deoxyribonucleoside; formed in nucleotide biosynthesis.
deoxyribose
A deoxypentose, 2-deoxy-d-ribose being the most common example, occurring in DNA and responsible for its name. - d. phosphate deoxyribonucleotide.
deoxyribosephosphate aldolase
An enzyme catalyzing cleavage of 2-deoxy-d-ribose 5-phosphate to d-glyceraldehyde 3-phosphate and acetaldehyde. SYN: deoxyriboaldolase.
deoxyriboside
Deoxyribose combined via its 1-O atom with a radical derived from an alcohol; not to be confused with deoxyribosyl compounds such as deoxyribonucleosides. Cf.:deoxyribosyl.
deoxyribosyl
The radical formed from deoxyribose by removal of the OH from the C-1 carbon; e.g., deoxyadenosine. Cf.:deoxyriboside.
deoxyribosyltransferases
Enzymes that catalyze the transfer of 2-deoxy-d-ribose from deoxyribosides to free bases.
deoxyribotide
Misnomer for deoxyribonucleotide or deoxynucleotide derived, by analogy with nucleoside-nucleotide, from incorrect usage of deoxyriboside.
deoxyribovirus
SYN: DNA virus.
deoxythymidine
SYN: thymidine.
deoxythymidylic acid
A component of DNA; originally and properly called thymidylic acid, but use of deoxy- is less ambiguous, as ribothymidylic acid is now known to exist. SYN: thymine ...
deoxyuridine
A derivative of uridine in which one or more of the hydroxyl groups on the ribose moiety has been replaced by a hydrogen; e.g., 2′-d. is a rare naturally occurring ...
deozonize
To deprive of ozone.
Department of Energy (DOE)
One of the U.S. government agencies contributing to the Human Genome Project.
Department of Health and Human Services
The United States government's principal agency for "protecting the health of all Americans and providing essential human services, especially for those who are least able to help ...
dependence
The quality or condition of relying upon, being influenced by, or being subservient to a person or object reflecting a particular need. [L. dependeo, to hang from] - anchorage d. ...
dependency
The state of being dependent. - pyridoxine d. with seizure an inherited disorder (autosomal recessive) apparently associated with deficient brain type I glutamate ...
Dependovirus
A genus of small defective single-stranded DNA viruses in the family Parvoviridae that depend on adenoviruses for replication. SYN: adeno- associated virus, adenosatellite virus. ...
depersonalization
A state in which one loses the feeling of one's own identity in relation to others in one's family or peer group, or loses the feeling of one's own reality. SYN: d. syndrome.
dephasing
In magnetic resonance imaging, following alignment by a radiofrequency pulse, the gradual loss of orientation of the magnetic atomic nuclei due to random molecular energy ...
dephosphorylation
Removal of a phosphoric group, usually hydrolytically and by enzyme action, from a compound.
Depigmentation
Loss of color (pigment) from the skin, mucous membranes, hair, or retina of the eye. The color of the skin, mucous membranes, hair, and retina is due to the deposition of ...
depilate
To remove hair by any means. Cf.:epilate. [L. de-pilo, pp. -atus, to deprive of hair, fr. de- neg. + pilo, to grow hair]
depilation
SYN: epilation.
depilatory
1. SYN: epilatory (1). 2. An agent that causes the falling out of hair. SYN: epilatory (2). - chemical d. a topically applied d. substance.
depletion
1. The removal of accumulated fluids or solids. 2. A reduced state of strength from too many free discharges. 3. Excessive loss of a constituent, usually essential, of the body, ...
Depo-Provera contraceptive
Injectable progestin (Depo-Provera) was approved by the U.S. Food and Drug Administration (FDA) for contraception in 1992. It is injected by a health professional into the ...
depolarization
1. A relative reduction in magnitude of polarization; in nerve cells, d. may result from an increase in the permeability of the cell membrane to sodium ions. 2. The ...
depolarize
To deprive of polarity.
depolymerase
Name used originally, before hydrolytic action was understood, for an enzyme catalyzing the hydrolysis of a macromolecule to simpler components. See nuclease.
deposit
1. A sediment or precipitate. 2. A pathological accumulation of inorganic material in a tissue. [L. de-pono, pp. -positus, to lay down] - brickdust d. a sediment of urates in ...
depravation
SYN: depravity. [L. depravatio, fr. depravo, pp. -atus, to corrupt]
depraved
Deteriorated or degenerate; corrupt. [L. depravo, to corrupt]
depravity
A depraved act or the condition of being depraved. SYN: depravation.
deprenyl
An inhibitor of monoamine oxidase selective for the type B isozyme. The drug is used as an antiparkinsonian agent. It does not give rise to the hypertensive crisis that can ...
depressant
1. Diminishing functional tone or activity. 2. An agent that reduces nervous or functional activity, such as a sedative or anesthetic. [L. de-primo, pp. -pressus, to press down]
depressed
1. Flattened from above downward. 2. Below the normal level or the level of the surrounding parts. 3. Below the normal functional level. 4. Dejected; lowered in spirits.
depression
1. Reduction of the level of functioning. 2. SYN: excavation (1). 3. Displacement of a part downward or inward. 4. A temporary mental state or chronic mental disorder ...
depressive
1. Pushing down. 2. Pertaining to or causing depression.
depressor
1. A muscle that flattens or lowers a part. 2. Anything that depresses or retards functional activity. 3. An instrument or device used to push certain structures out of the way ...
deprivation
Absence, loss, or withholding of something needed. - emotional d. lack of adequate and appropriate interpersonal or environmental experiences, or both, usually in the early ...
depsipeptide
An oligo- or polypeptide containing one or more ester bonds as well as peptide bonds. SEE ALSO: peptolide. [G. deseo, to knead, blend, + peptide]
depth
Distance from the surface downward. - anesthetic d. the degree of central nervous system depression produced by a general anesthetic agent; a function of potency of the ...
deptropine citrate
An antihistaminic agent with anticholinergic properties. SYN: dibenzheptropine citrate.
depulization
Destruction of fleas which convey the plague bacillus from animals to humans. [L. de, from, + pulex (pulic-), flea]
depurant
1. An agent or means used to effect purification. 2. An agent that promotes the excretion and removal of waste material. [L. de- intens. + puro, pp. -atus, to make pure]
depuration
Purification; removal of waste products or foul excretions.
depurative
Tending to depurate; depurant.
dequalinium acetate
An antimicrobial agent. SYN: decamine.
dequalinium chloride
Dequalinium acetate, with chloride replacing acetate, used as an antimicrobial agent primarily in lozenges for the treatment of mouth and throat infections.
deradelphus
Conjoined twins with a single head and neck and separate bodies below the thoracic level. See conjoined twins, under twin. [G. dere, neck, + adelphos, brother]
derailment
A symptom of a thought disorder in which one constantly gets “off the track” in one's thoughts and speech; similar to loosening of association.
deranencephaly, deranencephalia
1. Congenital malformation in which the head is absent, although there is a rudimentary neck. 2. Defect of the brain and upper part of the spinal cord. [G. dere, neck, + an-, ...
derangement
1. A disturbance of the regular order or arrangement. 2. Rarely used term for a mental disturbance or disorder. [Fr.]
Dercum
Francis X., U.S. neurologist, 1856–1931. See D. disease.
Dercum disease
A condition characterized by painful fatty tumors (lipomas) beneath the skin. The diseases tends to be associated with obesity and is about 5 times more frequent in females than ...
derealization
An alteration in one's perception of the environment such that things that are ordinarily familiar seem strange, unreal, or two-dimensional.
dereism
Mental activity in fantasy in contrast to reality. [L. de, away, + res, thing]
dereistic
Living in imagination or fantasy with thoughts that are incongruent with logic or experience.
derencephalia
SYN: derencephaly.
derencephalocele
In derencephaly, protrusion of the rudimentary brain through a defect in the upper cervical spinal canal. [G. dere, neck, + enkephalos, brain, + kele, hernia]
derencephaly
Cervical rachischisis and anencephaly, a malformation involving an open cranial vault with a rudimentary brain usually crowded back toward bifid cervical vertebrae. SYN: ...
derepression
A homeostatic mechanism for regulating enzyme production in an inducible enzyme system : an inducer, usually a substrate of a specific enzyme pathway, by combining with an ...
derivation
1. The source or process of an evolution. SYN: revulsion. 2. The drawing of blood or the body fluids to one part to relieve congestion in another. [L. derivatio, fr. derivo, ...
derivative
1. Relating to or producing derivation. 2. Something produced by modification of something preexisting. 3. Specifically, a chemical compound that may be produced from another ...
derm-, derma-
The skin; corresponds to L. cut-. See entries under cut. [G. derma]
dermabrader
A motor-driven device used in dermabrasion.
Dermabrasion
Dermabrasion is a surgical procedure that involves the controlled abrasion (wearing away) of the upper layers of the skin with sandpaper or other mechanical means. The purpose of ...
Dermacentor
An ornate, characteristically marked genus of hard ticks (family Ixodidae) that possess eyes and 11 festoons; it consists of some 20 species whose members commonly attack dogs, ...
Dermacoccus
A genus of Gram-positive, aerobic cocci found on human skin.
dermad
In the direction of the outer integument. [derm- + L. ad, to]
dermal
Relating to the skin. SYN: dermatoid (2).
Dermanyssus gallinae
The red hen-mite, a parasite of chickens, pigeons, and other birds; it sometimes attacks humans and causes an itching eruption, especially in sensitized individuals. SYN: Acarus ...
dermat-
The skin. SEE ALSO: derm-, dermato-, dermo-. [G. derma]
dermatalgia
Localized pain, usually confined to the skin. SYN: dermatodynia. [ dermat- + G. algos, pain]
Dermatitis
Inflammation of the skin, either due to direct contact with an irritating substance, or to an allergic reaction. Symptoms of dermatitis include redness, itching, and in some cases ...
Dermatitis and diarrhea, zinc deficiency
Among the consequences of zinc deficiency, dermatitis (skin inflammation) and diarrhea are particularly prominent features. A genetic disease called acrodermatitis enteropathica ...
Dermatitis, atopic
A skin disease characterized by areas of severe itching, redness, scaling, and loss of the surface of the skin (excoriation). When the eruption (rash) has been present for a ...
Dermatitis, stasis
A skin irritation on the lower legs, generally related to circulatory problems. Stasis refers to a stoppage or slowdown in the flow of blood (or other body fluid such as lymph). ...
dermato-
See derm-. [G. derma, skin]
dermatoarthritis
Associated skin disease and arthritis. - lipoid d. a multicentric reticulohistiocytosis.
Dermatobia
A genus of flies (family Oestridae) found in tropical America. [ dermato- + G. bios, way of living] - D. cyaniventris SYN: D. hominis. - D. hominis a large, blue, brown-winged ...
dermatobiasis
Infection of humans and animals with larvae of the fly Dermatobia hominis. SYN: human botfly myiasis.
dermatocellulitis
Inflammation of the skin and subcutaneous connective tissue.
dermatochalasis
A congenital or acquired condition characterized by deficient elastic fibers of the skin, which may hang in folds; vascular anomalies may be present; inheritance is either ...
dermatoconiosis
An occupational dermatitis caused by local irritation from dust. [ dermato- + G. konis, dust, + -osis, condition]
dermatocyst
A cyst of the skin.
dermatodynia
SYN: dermatalgia. [ dermato- + G. odyne, pain]
Dermatofibroma
A common type of benign skin tumor that is small, slow-growing, typically firm, red-to-brown and most often on the legs. Also called a fibrous histiocytoma. They can grow up to ...
dermatofibrosarcoma protuberans
A relatively slowly growing dermal neoplasm consisting of one or several firm nodules that are usually covered by dark red-blue skin, which tends to be fixed to the palpable ...
dermatofibrosis lenticularis disseminata
Small papules or discs of increased dermal elastic tissue appearing in early life; when osteopoikilosis is also present, the condition is called osteodermatopoikilosis or ...
dermatoglyphics
1. The configurations of the characteristic ridge patterns of the volar surfaces of the skin; in the human hand, the distal segment of each digit has three types of ...
dermatograph
The linear wheal made in the skin in dermatographism.
Dermatographism
A common form of hives that follows the repeated stroking, rubbing or scratching of the skin, or when tight-fitting clothes rub the skin. Dermatographism occurs in about 5% of ...
dermatoid
1. Resembling skin. SYN: dermoid (1). 2. SYN: dermal.
Dermatologist
: A doctor who specializes in the diagnosis and treatment of skin problems. * * * A physician who specializes in the diagnosis and treatment of cutaneous diseases and related ...
dermatology
The branch of medicine concerned with the study of the skin, diseases of the skin, and the relationship of cutaneous lesions to systemic disease. [ dermato- + G. logos, study]
dermatolysis
Loosening of the skin or atrophy of the skin by disease; erroneously used as a synonym for cutis laxa. SYN: dermolysis. [ dermato- + G. lysis, a loosening]
dermatoma
A circumscribed thickening or hypertrophy of the skin. [ dermato- + G. -oma, tumor]
Dermatome
: (1) A localized area of skin that is has its sensation via a single nerve from a single nerve root of the spinal cord. Shingles (herpes zoster) typically affects one or ...
dermatomegaly
Congenital or acquired defect in which the skin hangs in folds; may be part of a syndrome or may occur in isolation as cutis laxa, dermatochalasis, or dermatolysis. [ dermato- ...
dermatomere
A metameric area of the embryonic integument. [ dermato- + G. meros, part]
dermatomycosis
Fungus infection of the skin caused by dermatophytes, yeasts, and other fungi. Cf.:dermatophytosis. - d. pedis SYN: tinea pedis.
dermatomyoma
SYN: leiomyoma cutis. [ dermato- + G. mys, muscle, + -oma, tumor]
Dermatomyositis
A chronic inflammatory disease of skin and muscle which is associated with patches of slightly raised reddish or scaly rash. The rash can be on the bridge of the nose, around ...
dermatoneurosis
Any cutaneous eruption due to emotional stimuli.
dermatonosology
The science of the nomenclature and classification of diseases of the skin. [ dermato- + G. nosos, disease, + logos, treatise]
dermatopathia
SYN: dermatopathy. - d. pigmentosa reticularis SYN: livedo reticularis.
dermatopathology
Histopathology of the skin and subcutis, and study of the causes of skin disease.
Dermatopathy
Any disease of the skin. Synonymous with dermopathy. * * * Any disease of the skin. SYN: dermatopathia. [ dermato- + G. pathos, suffering]
Dermatophagoides pteronyssinus
A common species of cosmopolitan mites found in house dust and a common contributory cause of atopic asthma. [ dermato- + G. phago, to eat; ptero- + G. nysso, to prick, stab] ...
dermatophilosis
An infectious exudative dermatitis of cattle, sheep, goats, horses, and other animals (occasionally humans) caused by the bacterium Dermatophilus congolensis; severe (sometimes ...
Dermatophilus congolensis
A species of motile, nonacid fast, aerobic to facultatively anaerobic, Gram-positive bacteria that is the etiologic agent of dermatophilosis; also causes proliferative ...
dermatophobia
Morbid fear of acquiring a skin disease. [ dermatosis + G. phobos, fear]
dermatophylaxis
Protection of the skin against potentially harmful agents; e.g., infection, excessive sunlight, noxious agents. [ dermato- + G. phylaxis, protection]
dermatophyte
A fungus that causes superficial infections of the skin, hair, and/or nails, i.e., keratinized tissues. Species of Epidermophyton, Microsporum, and Trichophyton are regarded ...
dermatophytid
An allergic manifestation of dermatophytosis at a site distant from that of the primary fungous infection. The lesions, usually small vesicles on the hands and/or arms, are ...
dermatophytosis
An infection of the hair, skin, or nails caused by any one of the dermatophytes. The lesions may occur at any site on the body and, on the skin, are characterized by erythema, ...
dermatopolyneuritis
SYN: acrodynia (2).
dermatorrhagia
Hemorrhage from or into the skin. [ dermato- + G. rhegnymi, to break forth]
dermatorrhea
An excessive secretion of the sebaceous or sweat glands of the skin. [ dermato- + G. rhoia, flow]
dermatorrhexis
Rupture of the skin; e.g., as is seen in striae cutis distensae or in Ehlers-Danlos syndrome. [ dermato- + G. rhexis, rupture]
dermatoscopy
Inspection of the skin, usually with the aid of a lens or by epiluminescence microscopy, (q.v.). [ dermato- + G. skopeo, to view]
dermatosis
Nonspecific term used to denote any cutaneous abnormality or eruption. [ dermato- + G. -osis, condition] - acute febrile neutrophilic d. a rare d., predominant in women, of ...
dermatotherapy
Treatment of skin diseases.
dermatothlasia
An uncontrollable impulse to pinch and bruise the skin. [ dermato- + G. thlasis, a bruising]
dermatotropic
Having an affinity for the skin. SYN: dermotropic. [ dermato- + G. trope, a turning]
dermatozoon
An animal parasite of the skin. [ dermato- + G. zoon, animal]
dermatozoonosis
Infestation of the skin by an animal parasite. [ dermato- + G. zoon, animal, + nosos, disease]
dermatrophia, dermatrophy
Atrophy or thinning of the skin.
dermenchysis
Rarely used term for subcutaneous administration of remedies. [derm- + G. enchysis, a pouring in]
Dermicidin
A potent anti-infective agent that is a natural component of sweat. The first antimicrobial agent found that is produced by cells in the skin, dermicidin is reportedly active ...
Dermis
: The lower or inner layer of the two main layers of cells that make up the skin. * * * A layer of skin composed of a superficial thin layer that interdigitates with the ...
dermo-
See derm-. [G. derma, skin]
Dermobacter
A bacterial genus of nonmotile, non–spore-bearing Gram-positive rods, recovered on human skin. D. hominis has been associated with positive blood cultures.
dermoblast
One of the mesodermal cells from which the dermis is developed. [ dermo- + G. blastos, germ]
dermocyma
Unequal conjoined twins in which the smaller parasite is buried in the integument of the autosite. [ dermo- + G. kyma, fetus]
Dermoid
Also called a dermoid cyst of the ovary, this is a bizarre tumor, usually benign, in the ovary that typically contains a diversity of tissues including hair, teeth, bone, ...
Dermoid cyst of the ovary
A bizarre tumor, usually benign, in the ovary that typically contains a diversity of tissues including hair, teeth, bone, thyroid, etc. A dermoid cyst develops from a ...
dermoidectomy
Rarely used term for operative removal of a dermoid cyst. [ dermoid + G. ektome, excision]
dermolysis
SYN: dermatolysis.
dermonecrotic
Pertaining to any application or illness which may cause necrosis of the skin.
Dermopathy
Any disease of the skin. Synonymous with dermatopathy. * * * SYN: dermatopathy. - diabetic d. small macules and papules of the extensor surfaces of the extremities, most ...
dermophlebitis
Inflammation of the superficial veins and the surrounding skin. [ dermo- + G. phleps, vein, + -itis, inflammation]
dermoskeleton
SYN: exoskeleton (1).
dermostenosis
Pathologic contraction of the skin. [ dermo- + G. stenosis, a narrowing]
dermotoxin
A substance elaborated by a living agent, especially an exotoxin formed by bacteria, and characterized by its ability to cause pathologic changes in skin, e.g., erythema, ...
dermotropic
SYN: dermatotropic.
dermovascular
Pertaining to the blood vessel s of the skin. [ dermo- + L. vasculum, small vessel]
derodidymus
SYN: dicephalus diauchenos. [G. dere, neck, + didymos, twin]
derotation
1. A turning back. 2. In orthopedics, the correction of a rotation deformity by turning or rotating the deformed structure toward a normal position. [L. de, away, + rotatio, ...
DES
: Diethylstilbestrol, the earliest synthetic (man-made) form of a hormone in the estrogen class. DES was once widely prescribed to prevent miscarriages and premature births. Its ...
des-
In chemistry, a prefix indicating absence of some component of the principal part of the name; largely replaced by “de-” ( e.g., deoxyribonucleic acid, dehydro-) but ...
desamidize
SYN: deamidize.
desaturate
To produce desaturation.
desaturation
1. The act, or the result of the act, of making something less completely saturated; more specifically, the percentage of total binding sites remaining unfilled, e.g., when ...
Desault
Pierre-Joseph, French surgeon, 1744–1795. See D. bandage.
Descartes, Cartesius
René, French philosopher, mathematician, physiologist, 1596–1650. The founder of modern philosophy and proponent of the mechanistic school or iatromathematical school. See D. ...
Descemet
Jean, French physician, 1732–1810. See D. membrane.
descemetitis
Inflammation of Descemet membrane.
descemetocele
A bulging forward of Descemet membrane caused by the destruction of the substance of the cornea by infection.
descendens
SYN: descending. [L.] - d. cervicalis SYN: inferior root of ansa cervicalis. - d. hypoglossi SYN: superior root of ansa cervicalis.
descending
Running downward or toward the periphery. SYN: descendens. [L. de-scendo, pp. -scensus, to come down, fr. scando, to climb]
Descending aorta
The descending aorta is the part of the aorta, the largest artery in the body, that runs down through the chest and the abdomen. The descending aorta starts after the arch of the ...
Descending pathway
A nerve pathway that goes down the spinal cord and allows the brain to control movement of the body below the head. In contrast, ascending pathways are nerve pathways that go ...
descensus
A falling away from a higher position. SEE ALSO: ptosis, procidentia. SYN: descent (1). [L.] - d. testis descent of the testis from the abdomen into the scrotum during the ...
descent
1. SYN: descensus. 2. In obstetrics, the passage of the presenting part of the fetus into and through the birth canal. [L. descensus]
Deschamps
Joseph F.L., French surgeon, 1740–1824. See D. needle.
desensitization
1. The reduction or abolition of allergic sensitivity or reactions to the specific antigen (allergen). SYN: antianaphylaxis. 2. The act of removing an emotional complex. SYN: ...
desensitize
1. To reduce or remove any form of sensitivity. 2. To effect desensitization (1). 3. In dentistry, to eliminate or subdue the painful response of exposed, vital dentin to ...
deserpidine
Ester alkaloid isolated from Rauwolfia canescens (family Apocynaceae) with the same actions and uses as reserpine.
Desert fever
A disease also called coccidioidomycosis (CM) due to a fungus called Coccidioides immitis. About 40% of people infected with this fungus develop symptoms. Most often they have ...
desetope
That part of the Class II major histocompatibility molecule that interacts with the antigen. The term d. is derived from determinant selection. [determinant selection + -tope] ...
desferrioxamine mesylate
SYN: deferoxamine mesylate.
desflurane
An inhalation anesthetic with physical characteristics that provide rapid induction of and recovery from anesthesia.
deshydremia
Hemoconcentration due to the loss of water from blood plasma. [L. de-, away from, + G. hydor, water, + haima, blood + -ia]
desiccant
1. Drying; causing or promoting dryness. SYN: desiccative. 2. An agent that absorbs moisture; a drying agent. SYN: desiccator (1). SYN: exsiccant. [L. de-sicco, pp. -siccatus, ...
Desiccate
To remove the moisture from a thing that normally contains moisture, such as a plant; to dry out completely; to preserve by drying. The process of desiccating a thing is called ...
desiccation
The process of being desiccated. SYN: dehydration (4), exsiccation (1).
desiccative
SYN: desiccant (1).
desiccator
1. SYN: desiccant (2). 2. An apparatus, such as a glass chamber containing calcium chloride, sulfuric acid, or other drying agent, in which a material is placed for drying. - ...
Designer estrogen
An engineered drug that possesses some, but not all, of the actions of estrogen. Designer estrogens are selective estrogen-receptor modulators (SERMs). For example, raloxifene ...
desipramine hydrochloride
A dibenzazepine derivative; an antidepressant similar to imipramine hydrochloride. Selectively blocks reuptake of norepinephrine back into central aminergic neurons.
deslanoside
A rapidly acting steroid glycoside obtained from lanatoside C (Digitalis lanata) by alkaline hydrolysis; a cardiotonic.
desm-
See desmo-.
Desmarres
Louis A., French ophthalmologist, 1810–1882. See D. dacryoliths, under dacryolith, D. retractor.
desmin
Proteins found in intermediate filaments that copolymerizes with vimentin to form constituents of connective tissue, cell walls, filaments, etc. Found in Z disk of skeletal and ...
desmitis
Inflammation of a ligament. [ desm- + G. -itis, inflammation]
desmo-, desm-
Fibrous connection; ligament. [G. desmos, a band]
desmocranium
The mesenchymal primordium of the cranium.
desmodentium
The collagen fibers, running from the cementum to the alveolar bone, that suspend a tooth in its socket; they include apical, oblique, horizontal, and alveolar crest fibers, ...
desmodontium
SYN: desmodentium.
Desmodus
A blood-feeding genus of Chiroptera, known generally as vampire bats, found in Trinidad, Mexico, and Central and South America; D. artibaeus, D. rotundus, and D. rufus, three ...
desmogenous
Of connective tissue or ligamentous origin or causation; e.g., denoting a deformity due to contraction of ligaments, fascia, or a scar. [desmo- + G. -gen, producing]
desmography
A description of, or treatise on, the ligaments. [desmo- + G. grapho, to describe]
desmoid
1. Fibrous or ligamentous. 2. A nodule or relatively large mass of unusually firm scarlike connective tissue resulting from active proliferation of fibroblasts, occurring most ...
Desmoid tumor
Desmoid tumors are benign soft tissue tumors that occur most often in young adults and involve the limbs or trunk but can also arise in the abdomen or thorax. Desmoid tumors are ...
desmolases
Old and nonspecific term for enzymes catalyzing reactions other than those involving hydrolysis; e.g., those involving oxidation and reduction, isomerization, the breaking of ...
desmology
The branch of anatomy concerned with the ligaments. [desmo- + G. logos, study]
desmopathy
Any disease of the ligaments. [desmo- + G. pathos, suffering]
Desmoplasia
This term refers to the growth of fibrous or connective tissue. Some tumors elicit a desmoplastic reaction, the pervasive growth of dense fibrous tissue around the tumor. Scar ...
Desmoplastic
This term refers to the growth of fibrous or connective tissue. Some tumors elicit a desmoplastic reaction, the pervasive growth of dense fibrous tissue around the tumor. Scar ...
Desmoplastic reaction
This term refers to the growth of fibrous or connective tissue. Some tumors elicit a desmoplastic reaction, the pervasive growth of dense fibrous tissue around the tumor. Scar ...
desmopressin
An analog of vasopressin ( antidiuretic hormone, ADH) possessing powerful antidiuretic activity. - d. acetate a synthetic analog of vasopressin and an antidiuretic hormone.
desmosine
A cross-linking amino acid formed from lysyl residues found in elastin. [G. desmos, bond, fr. deo, to bind, + -ine]
desmosome
A site of adhesion between two epithelial cells, consisting of a dense attachment plaque separated from a similar structure in the other cell by a thin layer of extracellular ...
desmosterol
5α-Cholesta-5,24-diene-3β-ol; postulated intermediate in cholesterol biosynthesis from lanosterol via zymosterol; accumulates after prolonged administration of substances ...
desonide
An anti-inflammatory corticosteroid used in topical preparations.
desoximetasone
An anti-inflammatory corticosteroid used in topical preparations.
desoxy-
See deoxy-.
desoxycorticosterone
A steroid derived from the adrenal cortex with strong mineralocorticoid activity.
desoxycortone
SYN: deoxycorticosterone.
despeciation
1. Alteration of, or loss of species characteristics. 2. Removal of species-specific antigenic properties from a foreign protein.
despumation
1. The rising of impurities to the surface of a liquid. 2. The skimming off of impurities on the surface of a liquid. [L. de-spumo, pp. -atus, to skim, fr. spumo, to foam, fr. ...
Desquamate
To shed the outer layers of the skin. Although it may sound somewhat fishy, the word “desquamate” comes from the Latin “desquamare” meaning “to scrape the scales off a ...
Desquamation
The shedding of the outer layers of the skin. For example, once the rash of measles fades, there is desquamation. The word comes from the Latin “desquamare” meaning “to ...
desquamative
Relating to or marked by desquamation.
desthiobiotin
A compound derived from biotin by the removal of the sulfur atom; a precursor of biotin in bacteria and molds; it can substitute for biotin in some microorganisms, but is ...
destrudo
Energy associated with the death or destructive instinct. [coinage on the analogy of libido fr. L. destruo, to destroy]
desulfhydrases
Enzymes or groups of enzymes catalyzing the removal of a molecule of H2S or substituted H2S from a compound, as in the conversion of cysteine to pyruvic acid by cysteine ...
desulfinase
Term sometimes applied to the enzyme (aspartate-4-decarboxylase) removing sulfite : 1) from cysteinesulfinate, an intermediate in cysteine degradation, yielding alanine; 2) ...
Desulfotomaculum
A genus of rod-shaped (straight or curved), anaerobic, chemoorganotrophic motile bacteria that stain Gram-negative but have Gram-positive cell walls. Found in soil, the rumen and ...
desulfurases
SYN: desulfhydrases.
desynchronous
Lack of synchrony, as in brain waves. [de- + G. syn, with, + chronos, time]
DET
Abbreviation for diethyltryptamine.
det.
Abbreviation for L. detur, give. [let it be given]
detachment
1. A voluntary or involuntary feeling or emotion that accompanies a sense of separation from normal associations or environment. 2. Separation of a structure from its support. - ...
detection
1. The act of discovery. 2. In chromatography, visualization of the separated material.
detector
The component of a laboratory instrument which detects the chemical or physical signal indicating the presence or quantity of the substance of interest. - solid-state d. a d. that ...
detergent
1. Cleansing. 2. A cleansing or purging agent, usually salts of long-chain aliphatic bases or acids ( e.g., quaternary ammonium or sulfonic acid compounds) which, through a ...
deterioration
The process or condition of becoming worse. [L. deterior, worse] - alcoholic d. dementia occurring in persons chronically addicted to alcohol. See chronic alcoholism. - senile ...
determinant
The factor that contributes to the generation of a trait. [L. determans, determining, limiting] - allotypic determinants antigenic determinants of allotypes. - antigenic d. the ...
determination
1. A change, for the better or for the worse, in the course of a disease. 2. A general move toward a given point. 3. The measurement or estimation of any quantity or quality in ...
determinism
The proposition that all behavior is caused exclusively by genetic and environmental influences with no random components, and independent of free will. [L. determino, to limit, ...
detersive
SYN: detergent.
Detox
Short for detoxification, usually from an addictive drug such as alcohol or heroin. A detox center is designed to promote the recovery of a person from an addiction.
detoxicate
To diminish or remove the poisonous quality of any substance; to lessen the virulence of any pathogenic organism. SYN: detoxify. [L. de, from, + toxicum, poison]
detoxication
SYN: detoxification. - ammonia d. the d. of ammonia and ammonium ion by the formation of ammonium salts, specific nitrogen-excretion products, or l-glutamine.
detoxification
1. Recovery from the toxic effects of a drug. 2. Removal of the toxic properties from a poison. 3. Metabolic conversion of pharmacologically active principles to ...
Detoxify
To reduce or eliminate the toxicity of a substance or poison. To promote the recovery of a person from an addictive drug such as alcohol or heroin. * * * SYN: detoxicate.
detrition
A wearing away by use or friction. [L. de-tero, pp. -tritus, to rub off]
detritus
Any broken-down material, carious or gangrenous matter, gravel, etc. [L. (see detrition)]

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